Detoxification System
Your body has a sophisticated three-phase detoxification system. The microbiome plays a crucial role in each phase, particularly in preventing toxin reabsorption.
Phase I
Transformation
Cytochrome P450 Enzymes
Toxins are chemically modified to make them more reactive. The microbiome influences the expression of these liver enzymes.
Phase II
Conjugation
Making Toxins Water-Soluble
Modified toxins are bound to molecules (glutathione, sulfate, glycine) to make them water-soluble and easier to excrete.
Phase III
Elimination
Transport & Excretion
Conjugated toxins are actively transported out of cells and eliminated via urine or bile. Gut bacteria prevent reabsorption.
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Toxin In
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Eliminated